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All courses require permission of the instructor before registration can be completed.
GMS 6802 Health Outcomes Research for Chronic Diseases (3 credit hrs) GMS 6802 Syllabus
Description: In-depth analysis of risk factors and health outcomes assessment for adult and childhood chronic diseases.  The impact of childhood chronic conditions on adult health is emphasized. The interplay of health disparities and chronic diseases also will be discussed.
Prerequisite: GMS 6851
GMS 6803 Data Science for Clinical Research (3 credit hrs) GMS 6803 syllabus
Description: Students are introduced to the broad landscape of data science for biomedical and clinical research: learn how to design and implement computerized databases for data collection, perform basic query and reporting operations, prepare databases for analytical tasks, perform quality assurance procedures, and understand basic data analytical methods and approaches.
GMS 6804 Translational Bioinformatics (3 credit hrs) GMS 6804 syllabus
Description: Fundamental issues of bioinformatics and how they apply to translational and clinical problems. The course is organized in 4 parts: sequence analysis, databases and ontologies, genome-wide association and linkage analysis, and networks. Each part will cover the computing and mathematical concepts used, and motivated by the actual underlying bioinformatics questions.
Prerequisite: A graduate course in statistics
GMS 6805 Introduction to Applied Ontology (3 credit hrs) GMS 6805 syllabus
Description: Applied ontology is a sub-discipline of knowledge representation that develops resources to make the meaning of terms accessible to computers, to improve interoperability of data, and to support reasoning with digital knowledge bases. This course introduces students to the fundamentals of applied ontology and its role in biomedical informatics. Students will learn what ontologies are, how they differ from similar resources, and how to build, evaluate, and query ontologies. Students will also gain familiarity with a variety of ontologies and their application in biomedical informatics.
Prerequisite: None, but some experience with symbolic logic will be an asset.
GMS 6806 Security and Privacy in Clinical Research (3 credit hrs) GMS 6806 syllabus
Description: This course provides students with an introduction to a wide range of concepts, policies, and techniques in security and privacy (S&P) as they apply to biomedical and clinical research. Information security and data privacy are essential components of biomedical and clinical research. Students are introduced to the broad landscape of information security and data privacy for biomedical and clinical research: learn S&P related regulations and guidelines in clinical research, understand basic concepts of computer security, perform security analysis of a study’s security plan, learn best practice in secure data management (e.g., de-identification and encryption), and gain insight into state-of-the-art tools, methods, and approaches for the protection of information security and data privacy.
Prerequisite: None
GMS 6812 Health Outcomes Research in Cancer (3 credit hrs) GMS 6812 Syllabus
Description: Methods and measurement issues in cancer health outcomes assessment are  addressed across the continuum of cancer care  -prevention, screening, diagnosis, treatment, survivorship, and end of life.  Outcomes covered include survival, health-related quality of life, patient satisfaction with care, and economic burden.
Prerequisite: GMS 6851
GMS 6816 Pediatric Child Health Outcomes Assessment for Clinical and Community-Based Research (2 credit hrs)
Description: This course covers methods and measurement issues related to assessing children’s health outcomes in a range of clinical and community settings.  Issues such as assessing outcomes for children with special health care needs and healthy children, considerations related to growth and development, defining outcomes from parent, child and adolescent perspectives, the conduct of health risk assessments among adolescents, and implications for researchers and clinicians are presented.
Prerequisite: GMS 6851
GMS 6822 Measuring and Analyzing Health Outcomes (3 credit hrs) GMS 6822 syllabus
Description: This course provides instruction in the measurement methods currently used in health-related research in both clinical and community settings. The particular emphasis in this course is on cross-cultural translation of patient-reported outcomes measures and the development and use of measures for special populations such as children or those with chronic diseases.
GMS 6826 Advanced Design and Methodology for Case-Control Studies in Clinical Research (2 credit hrs)
Description: This course provides instruction on design, critical assessment, and implementation of case-control studies. This advanced course will focus on design and methodological challenges particularly important in case control studies. Variations of the case- control study including case series, case-crossover, case-cohort, and nested case-control studies will be covered.
GMS 6829 Longitudinal Research Design (2 credit hrs) GMS 6829 syllabus
Description: This course provides instruction in design, evaluation, and implementation of longitudinal research designs and focuses on evaluating the strengths and weaknesses of several designs as well as addressing other methodological issues.
Prerequisite: A graduate course in epidemiology, and a graduate course in statistics.
GMS 6832 Economic Methods for Evaluating Value in Health Care(3 credit hrs)
Description: This course covers economic methods for evaluating the relative value of health care interventions.   Foundational topics include framing the analysis, defining alternatives, techniques for eliciting patient preferences, measuring costs, and assessing outcomes. Students are exposed to cost effectiveness analysis and related methods for combining these core elements into an economic evaluation.
GMS 6833 Health Outcomes Research in Vulnerable Populations (3 credit hrs) GMS 6833 Syllabus
Description: Explore how the health care system in the United States serves vulnerable populations such as the poor, elderly, immigrants, racial and ethnic minorities, children and youth (especially those with chronic health conditions and disabilities) and young mothers. Emphasis is placed on health disparities within each of these vulnerable groups and health policy mechanisms to address critical issues facing these populations.
GMS 6834 Health Policy and the Formulation of Payment Mechanisms for Health Care (3 credit hrs)
Description: In this course, policy analytic tools are used to analyze payment mechanisms used in health care. Students gain an understanding of the evolution of physician and other provider reimbursement in health care throughout the twentieth century. Basic economic theory related to compensation and its application to the health care delivery system is presented.
GMS 6835 Health Outcomes Research in Children (3 credit hrs)
Description: This course uses policy analysis tools to examine critical issues in child health policy such as the development and funding of early intervention programs, the rise of new morbidities of childhood, and the health and insurance status of children in the United States. The impact of childhood conditions on adult health, health disparities in children and associated policy issues are addressed.
GMS 6842 Translational Research Methods (2 credit hrs)
Description: Concepts of translational research using a multidisciplinary approach to understand research design ranging from basic science discoveries to implementation of those discoveries in clinical and community settings.


GMS 6844 Time Series and Quasi-Experimental Design for Health Outcomes Research (2 credit hrs) GMS 6844 Syllabus
Description: This advanced graduate seminar-style course provides instruction in group-randomized trials and controlled quasi-experimental trials. Students will learn the four major types of validity used as the basis for evaluating the strength of a research trial, understand the strengths and limitations of different study designs, and discuss special considerations in group randomized trials.  At the end of the course, students will be able to plan, implement and critically evaluate group-randomized and quasi-experimental research trials, as well as evaluate the effects of natural experiments (e.g. policy changes).
Prerequisites: A graduate course in epidemiology, a graduate course in statistics, and permission of the instructor.
GMS 6846 Meta-Analysis in Clinical, Health Services Research, and Public Health (2 credit hrs)
Description: This course provides instruction in policy-related research method meta-analysis, the systematic reviewing of strategic summarized research evidence comprehensively and, when appropriate, quantitatively synthesized data from multiple studies.
GMS 6848 Ensuring Rigor and Reproducibility in Clinical and Translational Research (1 credit hr) GMS 6848 Syllabus
Description: Introduces best principles and practices required to conduct rigorous and reproducible research across the translational spectrum.  Topics will include sound study planning and design, consideration of all relevant biomedical variables, sound data management practices, statistical considerations and techniques, and transparency in reporting research results.
Prerequisites: GMS 6861
GMS 6850 Foundations of Biomedical Informatics (3 credit hrs) GMS6850 syllabus
Description: This course provides an overview of the principles and practices of health outcomes, health program evaluation, and implementation science in the context of the translational research continuum.  Content areas include the populations studied, data sources, and user audiences (e.g., the research community, health care practitioners, program directors, and community stakeholders).  Students are exposed to a range of health outcomes, program evaluation, and implementation science topics and conceptual frameworks.  Emphasis is placed on the importance of context (e.g., health care setting, family, community, culture, and socio-economic status) in conducting health outcomes research, program evaluation, and implementation science.
GMS 6851 Fundamentals of Dissemination and Implementation Research (3 credit hrs) GMS 6851 Syllabus
Description: This course provides an overview of the principles and practices of health outcomes, health program evaluation, and implementation science in the context of the translational research continuum. Content areas include the populations studied, data sources, and user audiences (e.g., the research community, health care practitioners, program directors, and community stakeholders). Students are exposed to a range of health outcomes, program evaluation, and implementation science topics and conceptual frameworks. Emphasis is placed on the importance of context (e.g., health care setting, family, community, culture, and socio-economic status) in conducting health outcomes research, program evaluation, and implementation science.
GMS 6852 Community Engaged Research for Clinical Effectiveness and Implementation Science Studies (2 credit hrs) GMS 6852 Syllabus
Description: This course covers the principles and practices of clinical effectiveness and implementation science research conducted with community partners. The benefits of and barriers to conducting community engaged research will be addressed in the context of the translational research continuum. The relationships between community partner involvement and study design, data collection, and analytic methods are addressed. Additional topics include partnership development, relationships between researchers and the community, capacity building, and sustainability.
Prerequisites: GMS 6851 and instructor approval
GMS 6853 Applied Topics in Dissemination and Implementation Science (2 credit hrs) GMS 6853 syllabus
Description: This course will enhance students’ knowledge of dissemination research and implementation science, which is the study of integrating evidence-based methods into health care policy and practice. A key focus will be on examining the strengths and limitations of different study designs in dissemination and implementation science, and the role of and strategies for engaging key stakeholders, including clinicians and policymakers, in the research process. Students will have an opportunity to apply methods they learn in the class through class discussions and presentations.
GMS 6854 Applied Topics in Clinical Effectiveness Research (2 credit hrs)
Description: Clinical effectiveness research advances the translation of evidence about the effectiveness of treatments and heath care delivery strategies into practice by assessing what interventions and strategies work best for which patients and in what settings are different treatment approaches best used. This course provides an overview of the origins of clinical effectiveness research, the role of clinical effectiveness research in the translational research spectrum, and the different study designs used for conducting clinical effectiveness research. Case studies, guest lectures by faculty engaged in clinical effectiveness research, and other applied approaches will be used.


GMS 6856 Introduction to Biomedical Natural Language Processing (3 credit hrs) GMS6856 Syllabus
Description: Introduces the basic knowledge of natural language processing (NLP), examines methods, systems, and ontologies/resources in the biomedical domain.  Students will gain necessary skills to process biomedical text, apply state-of-the-art NLP systems, and handle biomedical NLP tasks such as Information Extraction and Word Sense Disambiguation.
Prerequisites: Experience with computer programming, such as Python for data processing.
GMS 6885 Research Designs in Health Outcomes and Policy (3 credit hrs) GMS 6885 syllabus
Description: This course provides an overview of the research design of observational and experimental studies. This course will focus on critical assessment and methodological challenges important in health outcomes and policy studies. The course will provide foundation for Department of Health Outcomes and Policy advanced methods and policy electives.
Prerequisite: A graduate course in statistics
GMS 6893 Clinical and Translational Science Seminar Series (2 credit hrs) GMS 6893 syllabus
Description: This seminar series is designed to further the training of students in multi-disciplinary and inter-disciplinary clinical and translational research. Content areas include leading causes of morbidity and mortality in the United States, issues relevant to rural health and diseases such as HIV/AIDS and conditions such as obesity which have significant impact and research needs. The series consists of weekly, two-hour sessions which include researchers from the bench to the community. Specifically, for each topic area, speakers will discuss the clinical, laboratory, and epidemiological and economic aspects of the particular condition along with potential intervention strategies and community outreach activities.
GMS 6896 Health Outcomes and Policy Seminar (1 credit hr) GMS 6896 syllabus
Description: This interactive seminar series provides a forum for students and faculty to critically evaluate cutting-edge research and methodology and discuss the implications for their own research. Both recently published research and research in progress are evaluated.