Yi Guo

Yi Guo, Ph.D.

Associate Professor

Department: MD-HOBI-GENERAL
Business Phone: (352) 294-5969
Business Email: yiguo@ufl.edu

About Yi Guo

The increasing complexity of today’s biomedical research requires more than traditional, single point-of-view approaches. In particular, data-driven approaches that can reveal patterns in massive heterogeneous datasets and make clinically relevant predictions are becoming increasingly common in translational research. I have a strong, multi-disciplinary background in the analysis of real-world data such as those from the electronic health records (EHRs) and medical claims, data integration, predictive modeling, causal modeling and inference, mediation and moderation analysis, patient-reported outcomes, psychometric analysis, social media data analysis, and social media-delivered health interventions. Together, my areas of expertise serve an overarching research theme: data-driven precision health supporting clinical (shared) decision making and multilevel health interventions. Under the overarching theme, my research areas and expertise can be divided into four key methodologies: (1) EHR-based phenotyping and risk stratification – the identification of sub-populations with certain conditions or at higher risk for diseases; (2) Causal modeling and inference – the examination of causal relationships and pathways in clinical research, particularly treatment studies; (3) Patient-reported outcomes (PROs) in clinical and public health applications – the development, validation, assessment, analysis, and reporting of PROs among various populations, especially vulnerable populations; and (4) Social media analysis and social media-delivered intervention – mining social media data to study health behavior and health outcomes in various populations and developing social media-delivered interventions that promote public and consumer health.

Accomplishments

Exceptional Reviewer
2019 · The Journal of Rural Health
Exemplary Teacher Award
2019 · University of Florida College of Medicine
UF Health Shands Rose Rivers Chrysalis Award for Evolving Research
2019 · UF Health
Travel Award
2016 · The South Big Data Hub
Program Fellowship
2004 · Ohio State University, Ohio State Biochemistry Program

Teaching Profile

Courses Taught
2015-2018,2020-2022
GMS6822 Measuring and Analyzing Health Outcomes II
2019
GMS6812 Health Outcomes Research in Cancer
2017-2018
NGR7979 Advanced Research
2018
GMS7979 Advanced Research
2018
GMS7980 Research for Doctoral Dissertation
2018
NGR7980 Research for Doctoral Dissertation

Research Profile

My areas of expertise serve an overarching research theme: data-driven precision and public health supporting clinical (shared) decision making and multilevel health interventions. Under the overarching theme, my research areas and expertise can be divided into: 1) Electronic health records (EHR)-based phenotyping and risk stratification – the identification of sub-populations with certain conditions or at higher risk for diseases; 2) Causal modeling and inference – the examination of causal relationships and pathways in clinical and public health research, particularly treatment studies; 3) Patient-reported outcomes (PROs) in clinical and public health applications – the development, validation, assessment, analysis, and reporting of PROs among various populations, especially vulnerable populations; and 4) Social media analysis and social media-delivered intervention – mining social media data to study health behavior and health outcomes in various populations and developing social media-delivered interventions that promote public and consumer health.

Open Researcher and Contributor ID (ORCID)

0000-0003-0587-4105

Publications

2022
Procedural complications associated with invasive diagnostic procedures after lung cancer screening with low-dose computed tomography.
Lung cancer (Amsterdam, Netherlands). 165:141-144 [DOI] 10.1016/j.lungcan.2021.12.020. [PMID] 35124410.
2022
Syndromic Surveillance Systems for Mass Gatherings: A Scoping Review
International Journal of Environmental Research and Public Health. 19(8) [DOI] 10.3390/ijerph19084673. [PMID] 35457541.
2021
Bagged random causal networks for interventional queries on observational biomedical datasets.
Journal of biomedical informatics. 115 [DOI] 10.1016/j.jbi.2021.103689. [PMID] 33548542.
2021
Dental practitioners’ use of health risk assessments for a variety of health conditions
The Journal of the American Dental Association. 152(1):36-45 [DOI] 10.1016/j.adaj.2020.09.003. [PMID] 33276954.
2021
The application of artificial intelligence and data integration in COVID-19 studies: a scoping review
Journal of the American Medical Informatics Association. 28(9):2050-2067 [DOI] 10.1093/jamia/ocab098. [PMID] 34151987.
2021
The role of sex and rurality in cancer fatalistic beliefs and cancer screening utilization in Florida
Cancer Medicine. 10(17):6048-6057 [DOI] 10.1002/cam4.4122. [PMID] 34254469.
2020
Causal inference and counterfactual prediction in machine learning for actionable healthcare
Nature Machine Intelligence. 2(7):369-375 [DOI] 10.1038/s42256-020-0197-y.
2020
Objective and subjective socioeconomic status associated with metabolic syndrome severity among African American adults in Jackson Heart Study.
Psychoneuroendocrinology. 117 [DOI] 10.1016/j.psyneuen.2020.104686. [PMID] 32361636.
2020
Statin Use for Atherosclerotic Cardiovascular Disease Prevention Among Sexual Minority Adults
Journal of the American Heart Association. 9(24) [DOI] 10.1161/jaha.120.018233.
2019
ALOHA: developing an interactive graph-based visualization for dietary supplement knowledge graph through user-centered design
Bmc Medical Informatics and Decision Making. 19(4):1-18
2019
Assessing the effect of data integration on predictive ability of cancer survival models
.
2019
Association of Rates of Smoking During Pregnancy With Corporate Tobacco Sales Policies
Jama Pediatrics. 173(3):284-286
2019
Classification Tree Analysis of Factors Associated with Oral Cancer Exam
American Journal of Health Behavior. 43(3):635-647
2019
Facilitation or Hindrance: Physicians’ Perception on Best Practice Alerts (BPA) Usage in an Electronic Health Record System.
Health communication. 34(9):942-948 [DOI] 10.1080/10410236.2018.1443263. [PMID] 29485296.
2019
Low Rates of Patient-Reported Physician–Patient Discussion about Lung Cancer Screening among Current Smokers: Data from Health Information National Trends Survey
. 28(5):963-973
2019
Low Rates of Patient-Reported Physician–Patient Discussion about Lung Cancer Screening among Current Smokers: Data from Health Information National Trends Survey
Cancer Epidemiology Biomarkers & Prevention. 28(5):963-973 [DOI] 10.1158/1055-9965.epi-18-0629.
2019
Statistical thinking, machine learning
.
2019
The Wellness Incentive and Navigation intervention improved health‐related quality of life among Medicaid enrollees: A randomized pragmatic clinical trial
Health Services Research. 54(6):1156-1165 [DOI] 10.1111/1475-6773.13235. [PMID] 31642066.
2018
A 3-minute test of cardiorespiratory fitness for use in primary care clinics.
PloS one. 13(7) [DOI] 10.1371/journal.pone.0201598. [PMID] 30059539.
2018
An ontology-guided semantic data integration framework to support integrative data analysis of cancer survival.
BMC medical informatics and decision making. 18(Suppl 2) [DOI] 10.1186/s12911-018-0636-4. [PMID] 30066664.
2018
Assessing the added predictive ability of a metabolic syndrome severity score in predicting incident cardiovascular disease and type 2 diabetes: the Atherosclerosis Risk in Communities Study and Jackson Heart Study.
Diabetology & metabolic syndrome. 10 [DOI] 10.1186/s13098-018-0344-3. [PMID] 29796112.
2018
Dental Visits Mediate the Impact of Smoking on Oral Health
American Journal of Health Behavior. 42(1):59-68 [DOI] 10.5993/AJHB.42.1.6.
2018
Evaluating the reliability and validity of SF-8 with a large representative sample of urban Chinese
Health and Quality of Life Outcomes. 16(1) [DOI] 10.1186/s12955-018-0880-4. [PMID] 29615060.
2018
Metabolic syndrome severity is significantly associated with future coronary heart disease in Type 2 diabetes.
Cardiovascular diabetology. 17(1) [DOI] 10.1186/s12933-017-0647-y. [PMID] 29351794.
2018
New-Onset Diabetes Educator to Educate Children and Their Caregivers About Diabetes at the Time of Diagnosis: Usability Study
JMIR Diabetes. 3(2) [DOI] 10.2196/diabetes.9202. [PMID] 30291069.
2018
OC-2-KB: integrating crowdsourcing into an obesity and cancer knowledge base curation system.
BMC medical informatics and decision making. 18(Suppl 2) [DOI] 10.1186/s12911-018-0635-5. [PMID] 30066655.
2017
Assessing the Quality of Mobile Exercise Apps Based on the American College of Sports Medicine Guidelines: A Reliable and Valid Scoring Instrument
Journal of Medical Internet Research. 19(3) [DOI] 10.2196/jmir.6976. [PMID] 28270378.
2017
Assessment of Aphasia Across the International Classification of Functioning, Disability and Health Using an iPad-Based Application.
Telemedicine journal and e-health : the official journal of the American Telemedicine Association. 23(4):313-326 [DOI] 10.1089/tmj.2016.0072. [PMID] 27802112.
2017
Comparing and Contrasting A Priori and A Posteriori Generalizability Assessment of Clinical Trials on Type 2 Diabetes Mellitus.
AMIA … Annual Symposium proceedings. AMIA Symposium. 2017:849-858 [PMID] 29854151.
2017
Data Integration through Ontology-Based Data Access to Support Integrative Data Analysis: A Case Study of Cancer Survival.
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 2017:1300-1303 [DOI] 10.1109/BIBM.2017.8217849. [PMID] 29707415.
2017
Exploring the Association Between Self-Reported Asthma Impact and Fitbit-Derived Sleep Quality and Physical Activity Measures in Adolescents
JMIR mHealth and uHealth. 5(7) [DOI] 10.2196/mhealth.7346. [PMID] 28743679.
2017
Mobile Device Accuracy for Step Counting Across Age Groups
JMIR mHealth and uHealth. 5(6) [DOI] 10.2196/mhealth.7870. [PMID] 28659255.
2017
Using Social Media Data to Understand the Impact of Promotional Information on Laypeople’s Discussions: A Case Study of Lynch Syndrome
Journal of Medical Internet Research. 19(12) [DOI] 10.2196/jmir.9266. [PMID] 29237586.
2016
Validation of the Stroke and Aphasia Quality of Life Scale in a multicultural population.
Disability and rehabilitation. 38(26):2584-92 [DOI] 10.3109/09638288.2016.1138551. [PMID] 26860472.
2014
Speech pathology services for people with aphasia: what is the current practice in Singapore?
Disability and rehabilitation. 36(8):691-704 [DOI] 10.3109/09638288.2013.804597. [PMID] 23786347.
2008
The impact of dysarthria on everyday communication after traumatic brain injury: a pilot study.
Brain injury. 22(1):83-97 [DOI] 10.1080/02699050701824150. [PMID] 18183512.
New-Onset Diabetes Educator to Educate Children and Their Caregivers About Diabetes at the Time of Diagnosis: Usability Study (Preprint)
. [DOI] 10.2196/preprints.9202.
Using Social Media Data to Understand the Impact of Promotional Information on Laypeople�s Discussions: A Case Study of Lynch Syndrome (Preprint)
. [DOI] 10.2196/preprints.9266.

Grants

Jul 2021 ACTIVE
Comparative Effectiveness Research for Neuroendocrine Tumors (CER-NET)
Role: Principal Investigator
Funding: UNIV OF IOWA via PATIENT-CENTERED OUTCOMES RES INST
Apr 2021 ACTIVE
Optimizing the Population Representativeness of Older Adults in Cancer Trials
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Sep 2020 ACTIVE
Using Real-world Data to Assess the Burden of Diabetes in Children and Adolescents in Florida
Role: Principal Investigator
Funding: CTRS FOR DISEASE CONTROL AND PREVENTION
Aug 2020 ACTIVE
Optimizing the Population Representativeness of Older Adults in Alzheimer's Disease and Related Dementia Clinical Trials
Role: Co-Project Director/Principal Investigator
Funding: NATL INST OF HLTH NIA
Aug 2020 ACTIVE
Using Electronic Health Records from a Large Clinical Data Research Network to Understand Cancer Burden and Cancer Risks Among Transgender and Gender Nonconforming (TGNC) Individuals
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Mar 2020 – Mar 2021
Estimating and validating the necessary diagnostic cancer biomarker test characteristics and clinical utility in patients with indeterminant pulmonary nodules
Role: Principal Investigator
Funding: VANDERBILT UNIVERSITY MEDICAL CENTER via US FOOD AND DRUG ADMN
Jan 2020 – Aug 2020
The provision of research and evaluation to determine the short and long-term human health impacts from harmful algal blooms (HABs)
Role: Principal Investigator
Funding: FL DEPT OF HLTH
Jan 2020 ACTIVE
Extracting information from clinical narratives for Clinical Outcomes Research
Role: Co-Investigator
Funding: PATIENT-CENTERED OUTCOMES RES INST
Jan 2020 ACTIVE
The benefits and harms of lung cancer screening in Florida
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Jan 2020 – Mar 2020
Data Science in Health Informatics Workshop with Deep Learning Winter 2020
Role: Principal Investigator
Funding: *NORTHEASTERN UNIVERSITY OF CHINA
Jul 2019 – Sep 2019
Data Science in Health Informatics Workshop Summer 2019
Role: Principal Investigator
Funding: *NORTHEASTERN UNIVERSITY OF CHINA
Jan 2019 – Nov 2021
Systematic Analysis of Clinical Study Generalizability Assessment Methods with Informatics
Role: Co-Investigator
Funding: FL STATE UNIV via NATL INST OF HLTH NIA
Dec 2018 – Feb 2019
Data Science in Health Informatics Workshop Winter 2019
Role: Co-Investigator
Funding: *NORTHEASTERN UNIVERSITY OF CHINA
Jul 2018 ACTIVE
Implementing a Guidelines-Based M-Health Intervention for High Risk Asthma Patients
Role: Co-Investigator
Funding: ARKANSAS CHILDRENS RESEARCH INSTITUTE via NATL INST OF HLTH NINR
Jun 2018 – Dec 2018
2018 Data Science in Health Informatics Summer Workshop
Role: Principal Investigator
Funding: *NORTHEASTERN UNIVERSITY OF CHINA
Apr 2018 – Oct 2018
Stakeholder Engagement and Multi-Risk Assessment in Dental Care Settings
Role: Co-Investigator
Funding: UNIV OF ALABAMA BIRMINGHAM via NATL INST OF HLTH NIDCR
Apr 2017 – Mar 2018
The National Dental PBRN FY18
Role: Co-Investigator
Funding: UNIV OF ALABAMA BIRMINGHAM via NATL INST OF HLTH NIDCR
Sep 2016 – Sep 2017
PCORI Health Systems Demonstration Project OCHIN
Role: Co-Investigator
Funding: OCHIN via PATIENT-CENTERED OUTCOMES RES INST
May 2015 – Feb 2016
Testing Additional Pediatric Quality Measures: Extraction of Permanent Molar and Treatment in Sealed Occlusal Surface
Role: Principal Investigator
Funding: AMER DENTAL ASSO
Apr 2015 – Jun 2021
Clinical and Translational Science Institute (CTSI)
Role: Project Manager
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS
Jun 2014 – Dec 2017
OneFlorida Cancer Control Network
Role: Project Manager
Funding: FL DEPT OF HLTH BIOMED RES PGM/J&E KING

Education

Ph.D.
2009 · Ohio State University
B.S.
2002 · Wuhan University

Contact Details

Phones:
Business:
(352) 294-5969
Emails:
Business:
yiguo@ufl.edu
Addresses:
Business Mailing:
PO Box 100177
2004 MOWRY RD STE 2251
GAINESVILLE FL 32610