Yi Guo

Yi Guo, Ph.D.

Associate Professor

Department: MD-HOBI-GENERAL
Business Phone: (352) 294-5969
Business Email: yiguo@ufl.edu

About Yi Guo

The increasing complexity of today’s biomedical research requires more than traditional, single point-of-view approaches. In particular, data-driven approaches that can reveal patterns in massive heterogeneous datasets and make clinically relevant predictions are becoming increasingly common in translational research. I have a strong, multi-disciplinary background in the analysis of real-world data such as those from the electronic health records (EHRs) and medical claims, data integration, predictive modeling, causal modeling and inference, mediation and moderation analysis, patient-reported outcomes, psychometric analysis, social media data analysis, and social media-delivered health interventions. Together, my areas of expertise serve an overarching research theme: data-driven precision health supporting clinical (shared) decision making and multilevel health interventions. Under the overarching theme, my research areas and expertise can be divided into four key methodologies: (1) EHR-based phenotyping and risk stratification – the identification of sub-populations with certain conditions or at higher risk for diseases; (2) Causal modeling and inference – the examination of causal relationships and pathways in clinical research, particularly treatment studies; (3) Patient-reported outcomes (PROs) in clinical and public health applications – the development, validation, assessment, analysis, and reporting of PROs among various populations, especially vulnerable populations; and (4) Social media analysis and social media-delivered intervention – mining social media data to study health behavior and health outcomes in various populations and developing social media-delivered interventions that promote public and consumer health.

Accomplishments

Exceptional Reviewer
2019 · The Journal of Rural Health
Exemplary Teacher Award
2019 · University of Florida College of Medicine
UF Health Shands Rose Rivers Chrysalis Award for Evolving Research
2019 · UF Health
Travel Award
2016 · The South Big Data Hub
Program Fellowship
2004 · Ohio State University, Ohio State Biochemistry Program

Research Profile

My areas of expertise serve an overarching research theme: data-driven precision and public health supporting clinical (shared) decision making and multilevel health interventions. Under the overarching theme, my research areas and expertise can be divided into: 1) Electronic health records (EHR)-based phenotyping and risk stratification – the identification of sub-populations with certain conditions or at higher risk for diseases; 2) Causal modeling and inference – the examination of causal relationships and pathways in clinical and public health research, particularly treatment studies; 3) Patient-reported outcomes (PROs) in clinical and public health applications – the development, validation, assessment, analysis, and reporting of PROs among various populations, especially vulnerable populations; and 4) Social media analysis and social media-delivered intervention – mining social media data to study health behavior and health outcomes in various populations and developing social media-delivered interventions that promote public and consumer health.

Publications

2021
Bagged random causal networks for interventional queries on observational biomedical datasets.
Journal of biomedical informatics. 115 [DOI] 10.1016/j.jbi.2021.103689. [PMID] 33548542.
2020
Objective and subjective socioeconomic status associated with metabolic syndrome severity among African American adults in Jackson Heart Study.
Psychoneuroendocrinology. 117 [DOI] 10.1016/j.psyneuen.2020.104686. [PMID] 32361636.
2019
ALOHA: developing an interactive graph-based visualization for dietary supplement knowledge graph through user-centered design
Bmc Medical Informatics and Decision Making. 19(4):1-18
2019
Assessing the effect of data integration on predictive ability of cancer survival models
.
2019
Association of Rates of Smoking During Pregnancy With Corporate Tobacco Sales Policies
Jama Pediatrics. 173(3):284-286
2019
Classification Tree Analysis of Factors Associated with Oral Cancer Exam
American Journal of Health Behavior. 43(3):635-647
2019
Facilitation or Hindrance: Physicians’ Perception on Best Practice Alerts (BPA) Usage in an Electronic Health Record System.
Health communication. 34(9):942-948 [DOI] 10.1080/10410236.2018.1443263. [PMID] 29485296.
2019
Low Rates of Patient-Reported Physician–Patient Discussion about Lung Cancer Screening among Current Smokers: Data from Health Information National Trends Survey
. 28(5):963-973
2019
Statistical thinking, machine learning
.
2018
A 3-minute test of cardiorespiratory fitness for use in primary care clinics.
PloS one. 13(7) [DOI] 10.1371/journal.pone.0201598. [PMID] 30059539.
2018
An ontology-guided semantic data integration framework to support integrative data analysis of cancer survival.
BMC medical informatics and decision making. 18(Suppl 2) [DOI] 10.1186/s12911-018-0636-4. [PMID] 30066664.
2018
Assessing the added predictive ability of a metabolic syndrome severity score in predicting incident cardiovascular disease and type 2 diabetes: the Atherosclerosis Risk in Communities Study and Jackson Heart Study.
Diabetology & metabolic syndrome. 10 [DOI] 10.1186/s13098-018-0344-3. [PMID] 29796112.
2018
Dental Visits Mediate the Impact of Smoking on Oral Health
American Journal of Health Behavior. 42(1):59-68 [DOI] 10.5993/AJHB.42.1.6.
2018
Metabolic syndrome severity is significantly associated with future coronary heart disease in Type 2 diabetes.
Cardiovascular diabetology. 17(1) [DOI] 10.1186/s12933-017-0647-y. [PMID] 29351794.
2018
New-Onset Diabetes Educator to Educate Children and Their Caregivers About Diabetes at the Time of Diagnosis: Usability Study.
JMIR diabetes. 3(2) [DOI] 10.2196/diabetes.9202. [PMID] 30291069.
2018
OC-2-KB: integrating crowdsourcing into an obesity and cancer knowledge base curation system.
BMC medical informatics and decision making. 18(Suppl 2) [DOI] 10.1186/s12911-018-0635-5. [PMID] 30066655.
2017
Comparing and Contrasting A Priori and A Posteriori Generalizability Assessment of Clinical Trials on Type 2 Diabetes Mellitus.
AMIA … Annual Symposium proceedings. AMIA Symposium. 2017:849-858 [PMID] 29854151.
View on: PubMed
2017
Data Integration through Ontology-Based Data Access to Support Integrative Data Analysis: A Case Study of Cancer Survival.
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine. 2017:1300-1303 [DOI] 10.1109/BIBM.2017.8217849. [PMID] 29707415.
2017
Exploring the Association Between Self-Reported Asthma Impact and Fitbit-Derived Sleep Quality and Physical Activity Measures in Adolescents.
JMIR mHealth and uHealth. 5(7) [DOI] 10.2196/mhealth.7346. [PMID] 28743679.

Grants

Apr 2021 ACTIVE
Optimizing the Population Representativeness of Older Adults in Cancer Trials
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Sep 2020 ACTIVE
Using Real-world Data to Assess the Burden of Diabetes in Children and Adolescents in Florida
Role: Principal Investigator
Funding: CTRS FOR DISEASE CONTROL AND PREVENTION
Aug 2020 ACTIVE
Using Electronic Health Records from a Large Clinical Data Research Network to Understand Cancer Burden and Cancer Risks Among Transgender and Gender Nonconforming (TGNC) Individuals
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Aug 2020 ACTIVE
Optimizing the Population Representativeness of Older Adults in Alzheimer's Disease and Related Dementia Clinical Trials
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Mar 2020 – Mar 2021
Estimating and validating the necessary diagnostic cancer biomarker test characteristics and clinical utility in patients with indeterminant pulmonary nodules
Role: Principal Investigator
Funding: VANDERBILT UNIVERSITY MEDICAL CENTER via US FOOD AND DRUG ADMN
Jan 2020 – Aug 2020
The provision of research and evaluation to determine the short and long-term human health impacts from harmful algal blooms (HABs)
Role: Principal Investigator
Funding: FL DEPT OF HLTH
Jan 2020 ACTIVE
Extracting information from clinical narratives for Clinical Outcomes Research
Role: Co-Investigator
Funding: PATIENT-CENTERED OUTCOMES RES INST
Jan 2020 ACTIVE
The benefits and harms of lung cancer screening in Florida
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Jan 2020 – Mar 2020
Data Science in Health Informatics Workshop with Deep Learning Winter 2020
Role: Principal Investigator
Funding: *NORTHEASTERN UNIVERSITY OF CHINA
Jul 2019 – Sep 2019
Data Science in Health Informatics Workshop Summer 2019
Role: Principal Investigator
Funding: *NORTHEASTERN UNIVERSITY OF CHINA
Jan 2019 ACTIVE
Systematic Analysis of Clinical Study Generalizability Assessment Methods with Informatics
Role: Co-Investigator
Funding: FL STATE UNIV via NATL INST OF HLTH NIA
Dec 2018 – Feb 2019
Data Science in Health Informatics Workshop Winter 2019
Role: Co-Investigator
Funding: *NORTHEASTERN UNIVERSITY OF CHINA
Jun 2018 – Dec 2018
2018 Data Science in Health Informatics Summer Workshop
Role: Principal Investigator
Funding: *NORTHEASTERN UNIVERSITY OF CHINA
Apr 2018 – Oct 2018
Stakeholder Engagement and Multi-Risk Assessment in Dental Care Settings
Role: Co-Investigator
Funding: UNIV OF ALABAMA BIRMINGHAM via NATL INST OF HLTH NIDCR
Apr 2017 – Mar 2018
The National Dental PBRN FY18
Role: Co-Investigator
Funding: UNIV OF ALABAMA BIRMINGHAM via NATL INST OF HLTH NIDCR
Sep 2016 – Sep 2017
PCORI Health Systems Demonstration Project OCHIN
Role: Co-Investigator
Funding: OCHIN via PATIENT-CENTERED OUTCOMES RES INST
May 2015 – Feb 2016
Testing Additional Pediatric Quality Measures: Extraction of Permanent Molar and Treatment in Sealed Occlusal Surface
Role: Principal Investigator
Funding: AMER DENTAL ASSO
Apr 2015 – Jun 2021
Clinical and Translational Science Institute (CTSI)
Role: Project Manager
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS
Jun 2014 – Dec 2017
OneFlorida Cancer Control Network
Role: Project Manager
Funding: FL DEPT OF HLTH BIOMED RES PGM/J&E KING

Education

Ph.D.
2009 · Ohio State University
B.S.
2002 · Wuhan University

Teaching Profile

Courses Taught
2015-2018,2020-2021
GMS6822 Measuring and Analyzing Health Outcomes II
2019
GMS6812 Health Outcomes Research in Cancer
2017-2018
NGR7979 Advanced Research
2018
GMS7979 Advanced Research
2018
GMS7980 Research for Doctoral Dissertation
2018
NGR7980 Research for Doctoral Dissertation

Contact Details

Phones:
Business:
(352) 294-5969
Emails:
Business:
yiguo@ufl.edu