Muller Grants

2018

R25: A Master Course on Power for Multilevel and Longitudinal Health Behavior Studies

Muller, K.E. (Principal Investigator / Professor, Health Outcomes & Policy, University of Florida), Maldonado-Molina, M. (Co-Investigator / Associate Professor, Health Outcomes & Policy, University of Florida), Glueck, D. (Co-Investigator / Associate Professor, University of Colorado Denver), Kreidler, S. (Co-Investigator / Biostatistician, University of Colorado Denver). NIH. 8/26/14– 6/30/18. Award amount: $1,005,962.

This project will be composed of a diverse and highly qualified team including experts in biostatistics, social and behavioral science, software engineering, minority recruitment, and educational technology to develop, implement, evaluate, and disseminate a short course entitled “A Master Course on Power for Multilevel and Longitudinal Health Behavior Studies.”

2017

G13: Power and Sample Size for Multilevel and Longitudinal Designs in Health Research

Muller, K.E. (Principal Investigator / Professor, Health Outcomes & Policy, University of Florida), Glueck, D. (Co-Investigator / Associate Professor, University of Colorado Denver). NIH. 9/28/14– 9/27/17. Award amount: $150,000.

This project will be composed of two experts in multilevel and longitudinal power and sample size to create a book-length, peer-reviewed, scholarly work entitled “Power and Sample Size for Multilevel and Longitudinal Designs in Health Research.” The two investigators will share authorship with an expert team of statisticians specializing in sample size methods.

Corpus Luteal Contribution to Maternal Pregnancy Physiology and Outcomes in ART

Conrad, K.P. (Principal Investigator / Professor, Department of Physiology and Functional Genomics, University of Florida), Muller, K.E. (Co-Investigator, Biostatistician / Professor, Health Outcomes & Policy, University of Florida). NIH. 9/27/11– 2/28/17. Award amount: $6,292,692.

This project will investigate the corpus luteal contribution to maternal pregnancy physiology and outcomes in ART using fundamental, clinical, and epidemiological approaches. Its successful completion will provide novel and groundbreaking insights into the maternal physiology of ART and spontaneously conceived pregnancies, as well as the adverse pregnancy outcomes of ART.

2015

Vitamin B6 Effects on One-Carbon Metabolism

Gregory, J. (Principal Investigator / Professor, Food Science and Human Nutrition, University of Florida), Muller, K. (Principal Investigator / Professor, Health Outcomes & Policy, University of Florida). NIH. 12/9/10– 11/30/15. Award amount: $3,588,421.

The long-term goals of this project are to determine by kinetic and metabolomic methods the functional metabolic consequences of low vitamin B6 nutritional status in women using oral contraceptives, determine the effect of vitamin B6 repletion, and gain new mechanistic and quantitative insights into the interrelationships between 1C metabolism, transsulfuration and glutathione synthesis, gluconeogenesis, provide information relevant to functional nutritional status assessment and vitamin B6 requirements, and to gain insight into relationships between in vivo metabolic fluxes and metabolite profiles through integrated kinetic and metabolomic analysis.

2014

Multilevel and Longitudinal Study Sample Size Tools for Behavioral Scientists

Muller, K.E. (Principal Investigator / Professor, Health Outcomes & Policy, University of Florida), Maldonado-Molina, M. (Co-Investigator / Associate Professor, Health Outcomes & Policy, University of Florida), Logan, H. (Co-Investigator / Professor, Department of Community Dentistry and Behavioral Science, University of Florida), Glueck, D. (Co-Investigator / Associate Professor, University of Colorado Denver), Kreidler, S. (Co-Investigator / Biostatistician, University of Colorado Denver). NIH. 12/9/10– 11/30/14. Award amount: $2,167,123.

The ethics and cost of human research demand accurate sample sizes. Current sample size selection methods can fail with multilevel and longitudinal data. The goals of this project are to develop new sample size tools for behavioral scientists conducting prevention research in communities with diverse populations.

Southeast Center for Research to Reduce Disparities in Oral Health

Logan, H. (Principal Investigator / Professor Emeritus, Department of Community Dentistry and Behavioral Science, University of Florida), Muller, K.E. (Co-Investigator / Professor, Health Outcomes & Policy, University of Florida). NIH. 9/19/08– 5/31/14. Award amount: $5,286,130.

This is a multi-disciplinary center to foster research disparities in cancer survival by promoting early detection of oral and pharyngeal cancer through two community based theoretically derived intervention projects.

2012

Ancillary Functional Studies for the Cardiovascular Cell Therapy Research Network

Pepine, C. (Principal Investigator), Muller, K.E. (Co-Investigator / Professor, Health Outcomes & Policy, University of Florida). NIH/NHLBI. 9/30/08– 7/31/12. R01 HL091005. Award amount: $1,480,565.

The Etiology of Alcohol Use and Consequences Among Multi-Ethnic Urban Youth

Komro, K. (Principal Investigator / Professor, Health Outcomes & Policy, University of Florida), Maldonado-Molina, M. (Co-Investigator / Associate Professor, Health Outcomes & Policy, University of Florida), Wagenaar, A. (Co-Investigator / Professor, Health Outcomes & Policy, University of Florida), Muller, K.E. (Co-Investigator / Professor, Health Outcomes & Policy, University of Florida), Tobler, A. (Co-Investigator). National Institute of Health/NIAAA. 5/10/08– 4/30/12. R01 AA016549. Award amount: $1,899,024.