Muller, Keith

Professor, Department of Health Outcomes & Biomedical Informatics
Faculty, Institute for Child Health Policy

Phone: (352) 294-5967
Fax: (352) 294-5994
University of Florida

Clinical and Translational Research Building
2004 Mowry Road, Suite 2246
PO Box 100177
Gainesville, FL 32610-0147


Professional Biography

Professor Muller has NIH funding from NIGMS, NLM, and NCATS. His journal publications are split roughly equally between scientific collaborations and biostatistical methodology developments. In addition, Professor Muller is the first author of two current books on the theory and practice of linear models.

Professor Muller serves as co-principal investigator of 9R01GM121081-05, “Methods and Software for Lifecourse Epidemiology Data and Sample Size Analysis” funded by NIH/NIGMS, 08/15/2016-06/30/2020, as a continuation of 1R01DE020832-01A1. Co-principal investigators are Dr. D. H. Glueck (UCD) and Dr. D. Dabelea (UCD). Dr. Muller (UF) and Dr. D. H. Glueck (UCD) are co-PI of 1R25GM111901-01, “A Master Course on Power for Multilevel and Longitudinal Health Behavior Studies,” funded by NIH/OBSS and NIGMS, 08/25/2014-06/30/2018, and also 1G13LMO11879-01, “Guidebook to Power and Sample Size for linear models,” funded by NLM/NIH, 12/01/2014-11/30/2016.

Personal Methodology Research

Professor Muller’s current research centers on power and sample size for multilevel and longitudinal designs, especially with trajectories as predictors. He and colleagues also pursue advances in adaptive designs and High Dimension, Low Sample Size (more variables than participants).

Keith Muller CV


  • Biostatistics
  • Health outcomes research
  • Statistical methods

Software has many resources including free software for power and sample size for multilevel and longitudinal designs, as well as associated tutorials, documentation, articles, and special purpose software.


Refereed Articles
  • Cardel MI, Johnson SL, Beck J, Dhurandhar E, Keita AD, Tomczik AC, Pavela G, Huo T, Janicke DM, Muller K, et al. The effects of experimentally manipulated social status on acute eating behavior: A randomized, crossover pilot study. 2016 Apr 16. Physiological Behavior, 162, 93-101. PMCID: PMC4899290
  • Thompson LA, Wegman M, Muller KE, Muszynski M, Rathore M, De Leon J, Shenkman EA and the Health IMPACTS for Florida Network (2016) Improving adolescent health risk assessment: a multi-method pilot study. Maternal and Child Health Journal. DOI 10.1007/s10995-016-2070-5135 PMID: 27406154 [PubMed – in process]
  • Ringham BA, Kreidler SM, Muller KE, Glueck DH (2016). Multivariate test power approximations for balanced linear mixed models in studies with missing data. Statistics in Mededicine, 35, 2921-2937. PMCID: PMC4879605
  • Shenkman E, Muller K, Vogel B, Nixon SJ, Wagenaar AC, Case K, Guo Y, Wegman M, Aric J and Stoner D (2015) The wellness incentives and navigation project: design and methods. BMC Health Services Research, 15 (579). PMCID: PMC4696169
  • Johnson JL, Kreidler SM, Catellier DJ, Murray DM, Muller KE, Glueck DH (2015) Recommendations for choosing an analysis method that controls Type I error for unbalanced cluster sample designs with Gaussian outcomes. Statistics in Medicine, doi: 10.1002/sim.6565. [Epub ahead of print] PubMed PMID: 26089186.